Mohammad Hossein Kariminasab - MD, Assistance professor Department of Orthopedic Surgery, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Masoud Shayeste-Azar - MD, Assosiated professor, Department of Orthopedic Surgery, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Mohamad Hossein Kariminasab - MD, Assosiated professor, Department of Orthopedic Surgery, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Majid Sajjadi Saravi - MD, Assistance professor Department of Orthopedic Surgery, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

Osteogenesis Imperfecta (OI) or Brittle bone disease, is a rare genetic disorder that causes type Icollagen synthesis disturbance results in bone fragility.We present a female newborn which had numerous fractures in the arm and femur. Her delivery was at38 weeks gestation by caesarean section. Prenatal ultrasound revealed bone swelling and long bonesshortness. The patient is pale blue sclera. 36 days after birth, the patient had a fracture in her left femur.Genetic analysis of the patient was reported. Protests by clinical, ultrasound and x-ray taken duringpregnancy for this patient reported Osteogenesis Imperfecta type V.shortening, swelling and deformity of the long bones during prenatal sonography can prove OsteogenesisImperfecta before birth and select the correct orthopedic plan for treatment.

Osteogenesis Imperfecta, multiple fractures, collagen type I