Fe۳O۴@TiO۲@V۲O۵ as an Efficient Magnetic Nanoparticle for Synthesis of Di-Indolyl Oxindole Derivatives

In this work, Fe۳O۴@TiO۲@V۲O۵ is synthesized via functionalization of Fe۳O۴ with TiO۲ and then modifying with V۲O۵. The characterization of the synthesized nano-catalyst is performed using several methods including XRD, TEM, SEM, EDS, TGA, and VSM. This nano-catalyst impressively catalyzes the synthesis of ۳,۳-di-indolyl oxindoles (with an ۸۵-۹۸% yield in ۱۰-۸۰ minutes). Furthermore, the introduced catalyst can be reused in at least five successive reactions with no significant catalytic activity loss. The effects of some influencing parameters on the catalytic efficacy of Fe۳O۴@TiO۲@V۲O۵ are also assessed. The appropriate product is attained for a wide range of isatins and indoles. Using an inexpensive and reusable catalyst and using the H۲O solvent puts this methodology in the green chemistry domain.

کلیدواژه ها:

Magnetic nanoparticles ، Fe۳O۴@TiO۲@V۲O۵ ، green chemistry ، inexpensive and reusable catalyst ، eco-friendly catalyst