Label-Free Perfect Separation of Michigan Cancer Foundation-۷ Cells from White Blood Cells using Both Wall-Induced Lift and Dielectrophoresis Forces

A microchannel device was designed and utilized to separate Michigan Cancer Foundation-۷ cells from white blood cells using both wall-induced lift and di-electrophoresis forces. Using COMSOL Multiphysics simulator, the label-free separation process is performed based on the radius size of the particles. The best performance of the structure is obtained with the efficiency of ۱۰۰% and ۹۹% for cancer and white blood cells separation processes, respectively. For the proposed microfluidic structure, in addition to the highest available efficiency and high separation speed of ۱۲ um/s, the low DC voltage of ۶ V is applied, which causes negligible damage to the blood cells.

کلیدواژه ها:

Cancer cells ، COMSOL ، Dielectrophoresis ، Microfluidics ، separation