The estimate of average age at the onset of acute myocardial infarction in Iran: A systematic review and meta-analysis study

BACKGROUND: Research indicates that the age of onset of first acute myocardial infarction (AMI) is an essential element in the life expectancy that has been decreasing in developing countries. There are various studies performed in Iran reporting a range of ages at time of AMI. Thus, this meta-analysis study is designed to determine the mean age at first AMI in the Iranian population.METHODS: All studies that met the inclusion and exclusion criteria were reviewed using standard keywords in the databases from ۲۰۰۰ to ۲۰۱۶. Two raters verified a total of ۶۵۸ articles. Sixteen studies met the inclusion criteria of this study for meta-analysis. Cochran test and I-squared (I۲) were used for samples’ homogeneity. Pooled estimates of mean were calculated using the random effects inverse-variance model.RESULTS: The mean age of AMI varied between ۵۵.۹ to ۶۲.۹ years among the primary studies. The pooled mean age of first AMI with a ۹۵% confidence interval (CI) for the total sample, men, and women were ۵۹ (۵۸.۹, ۶۰.۴), ۵۸.۷ (۵۸.۳, ۵۹.۲), and ۶۴.۲ (۶۳.۵, ۶۴.۸), respectively.CONCLUSION: Our meta-analysis shows that the mean age of first onset of AMI in Iranian people is slightly lower than that reported elsewhere; and it is lower for men than for women.

کلیدواژه ها:

Myocardial Infarction ، Meta-Analysis ، Iran