Effects of Purslane Supplementation on Blood Lipid Profile: A Systematic Review and Meta-analysis of Randomized Controlled Trials
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 225
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شناسه ملی سند علمی:
JR_JKMU-29-6_011
تاریخ نمایه سازی: 19 دی 1401
چکیده مقاله:
Background: Blood lipid profiles are known as one of the most important factors in health disorders such as obesity and diabetes, which mostly end in cardiovascular diseases (CVDs) such as coronary heart disease (CHD). Purslane, as an edible herbal plant has shown to have beneficial components for dyslipidemia treatment. This study aimed to evaluate the effects of purslane supplementation on blood lipid profiles in the adult population.Methods: The terms Portulaca, Portulaca, Portulaca oleracea, and Purslane together with lipid profile ingredients including triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were searched in the following databases until ۳۰ October ۲۰۲۰: PubMed, MEDLINE, Scopus, EMBASE, Science Direct, and SID. A meta-analysis was conducted with eight randomized controlled trials (RCTs) on ۴۴۴ patients using the STATA software version ۱۴.Results: Eight eligible studies on ۴۴۴ patients were identified for the present study. The purslane supplementation caused significant reduction in TG (-۱۸.۵۵ mg/dL, ۹۵% CI [-۳۱.۷۱۲, -۵.۳۸۸]), TC (-۸.۴۳ mg/dL; ۹۵% CI [-۱۴.۹۹, -۱.۸۷]), and LDL-C (-۶.۴۵ mg/dL, ۹۵% CI [-۱۱.۱۳, -۱.۷۷]); however, no significant effect was observed on HDL-C (۱.۲۸ mg/dL, ۹۵% CI [-۰.۵۶, ۲.۹۳], P = ۰.۱۷۰).Conclusion: Our results suggested that purslane supplementation could reduce TG, TC, and LDL-C. However, no significant effect was observed on HDL-C.
کلیدواژه ها:
نویسندگان
Behrouz Talaei
Student Research Committee, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran & Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
Sina Ravari
Student Research Committee, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran & Department of Nutrition, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
Marieh Salavatizadeh
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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