Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial

سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 146

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شناسه ملی سند علمی:

JR_AJP-13-2_003

تاریخ نمایه سازی: 6 اسفند 1401

چکیده مقاله:

Objective: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia.Materials and Methods: This randomized controlled clinical study was carried out on ۴۰ patients with total cholesterol >۲۰۰ mg/dl, triglycerides >۱۵۰ mg/dl and BMI >۲۵, of either sex, aged ۳۰-۵۰ years, who were recruited through written consent. The patients were divided into two groups (n=۲۰ each): the ADP and the control group (CG). All patients received the doctor’s prescribed class A statin (Rosuvastatin/ Atorvastatin) ۱۰ mg/day, while ۲.۷ g ADP was given on daily basis before breakfast with lukewarm water for ۴۰ days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after ۲۰ and ۴۰ days. Data were analyzed by using SPSS and GraphPad Prism.Results: ADP significantly reduced body weight (p<۰.۰۰۱), BMI (p<۰.۰۰۱), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=۰.۰۰۰) decreased the serum level of total cholesterol and low-density lipoprotein. Conclusion: ADP may have the potential to improve dyslipidemia and obesity.

کلیدواژه ها:

نویسندگان

Parkha Nasrullah

Department of Human Nutrition, University of Agriculture Peshawar, KP Pakistan

Bismillah Sehar

Department of Health and Social Sciences, University of Bedfordshire, UK

Mahpara Safdar

Department of Environmental Design, Health and Nutritional Sciences, Faculty of Sciences, Allama Iqbal Open University Islamabad, Pakistan

Sadia Fatima

Department of Biochemistry, Khyber Medical University, Peshawar, Pakistan

Falak Zeb

Sharjah Institute for Medical Research, University of Sharjah, United Arab Emirates

Jahan Shah

Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China

Atif Khan

Department of Biological Sciences, National University of Medical Sciences, Rawalpindi- Pakistan

Bilal Ahmed

Department of Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu Province, PR China

Ali Alsubaie

Department of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia

Muhammad Zaman

Nan Shi Fu Zhong (NSFZ), Nanjing Normal University, Nanjing-China