Synthesis of Bis-۴-hydroxycoumarins via a Multi Component Reaction Using Silica Boron-sulfuric Acid Nanoparticles (SBSANs) as an Efficient Heterogeneous Solid Acid Catalyst
محل انتشار: دوفصلنامه تحقیقات شیمی آلی، دوره: 2، شماره: 2
سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 62
فایل این مقاله در 14 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ORGC-2-2_007
تاریخ نمایه سازی: 3 مهر 1402
چکیده مقاله:
The silica boron sulfuric acid nanoparticles (SBSANs) as an efficient heterogeneous solid acid catalyst with both Brønsted and Lewis acidic sites catalyzed the preparation of bis-۴-hydroxycoumarin derivatives using reaction of aldehydes and ۴-hydroxycoumarin under mild and solvent-free condition at room temperature. This new and efficient methodology has advantages in comparison with currently used methods such as: easy work-up, simple separation of catalyst from the reaction mixture, reusability and lower catalyst loading, relatively short reaction time, eco-friendly with environment, excellent yields, simple purification of products and mild reaction condition. Using this method a range of biologically active bis-۴-hydroxycoumarin derivatives were synthesized in good to excellent yield. The catalyst system was reusable at least for ۵ times in this reaction without significant decreasing in its catalytic activity.
کلیدواژه ها:
نویسندگان
Habib Ollah Foroughi
Department of scince, Islamic AZad University, Fasa branch
Ali Khalafi-Nezhad
Department of Chemistry, Shiraz University, Shiraz,۷۱۴۵۴, I.R.Iran