‎In vitro‎ assessment of anti-Trichomonas effects of Zingiber officinale and ‎Lavandula angustifolia alcoholic extracts on Trichomonas gallinae

Trichomonas gallinae is a parasite that acts as a canker-causing agent and leads to significant loss and mortality, especially in young birds. Metronidazole is the approved drug used for the treatment of trichomoniasis. A non-chemical alternativess such as medical plant extracts are also used to treat this disease due to drug resistance. This study aimed to assess in vitro antitrichomonal effects of Lavandula angustifolia and Zingiber officinale extracts on T. gallinae compared with metronidazole. The T. gallinae samples were obtained from infected pigeons. Multi-well plates filled with different concentrations (۵.۰۰, ۱۰.۰۰, ۲۵.۰۰, ۵۰.۰۰, and ۱۰۰ μg mL-۱) were used to perform in vitro analysis. The Z. officinaleextract’s minimum inhibitory concentration (MIC) in the ۲۴-hr period was ۲۵.۰۰ μg mL-۱, while it was ۵۰.۰۰ μg mL-۱ for metronidazole. The MIC value obtained for L. angustifolia extract in ۲۴-hr was ۵۰.۰۰ μg mL-۱. The results indicated that the extracts of Z. officinaleand L. angustifolia could act as potential natural agents against trichomoniasis. Furthermore, this study delineated the equal efficiency of L. angustifolia and Z. officinale with that of metronidazole in inhibiting the growth of Trichomonas gallinae trophozoites in culture media.

کلیدواژه ها:

‎ In vitro ، ‎ Ginger ، ‎ Lavender ، ‎ Trichomonas gallinae