بررسی تاثیر تزریق گلوکز هیپرتونیک بر کفایت دیالیز در بیماران غیردیابتیک تحت همودیالیز

Abstract Aims: H emodialysis Patients suffer from many problems and complications during disease and their treatment.One of the most important and common problems is hypotension and dialysis adequacy.This study has been designed and implemented to determine the effect of hypertonic glucose on dialysis adequacy and blood pressure in non-diabetic dialysis patients. Methods: The present study was a quasi-experimental and single group study that ۴۵ none-diabetic hemodialysis patients from the chosen hospitals were selected and hypertonic glucose infused patients for two weeks and three times a week, after two weeks durability, patients were assessed without manipulation for two weeks. In addition blood pressureand dialysis adequacy of the patients were measured in manipulation phase before and after each infusion of hypertonic glucose .Data collection tools included demographic information and dialysis adequacy was calculated by Daugirdasformula at the end of every stage in two study environments.then the data were analyzed by using SPSS ۱۷ software and descriptive statistical tests (abundance- mean),inferential tests (paired t test, mane Whitney, Friedman, Kruskal-wallis and wilcoxon) Results: The results showed thatdialysis adequacyand also blood pressure of the patients had been increased significantly in manipulation phase ( p=۰.۰۰۱ ). Andanalysis of data between the gender (p=۰.۰۰۱) and vascular access ( p=۰.۰۰۱ ) showed significant differences ( p=۰.۰۰۱ ),but inother cases , there was no significant difference. Conclusion:results of this study showed thatinjection of hypertonic glucose increased dialysis adequacy in hemodialysis patients significantly and prevented hypotension.

کلیدواژه ها:

Dialysis Adequacy ، Hemodialysis ، Hypertonic Glucose ، همودیالیز ، کفایت دیالیز ، گلوکز هیپرتونیک