Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 30
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شناسه ملی سند علمی:
JR_HERM-12-2_001
تاریخ نمایه سازی: 14 آذر 1402
چکیده مقاله:
This overview on Volkameria inermis (Lamiaceae) is the first in updating information on the chemical constituents and pharmacological properties of the species, notably on its unique ability in ameliorating motor tics. The information was procured from Google, Google Scholar, PubMed, PubMed Central, Science Direct, J-Stage, and PubChem. Previously named Clerodendrum inerme (Verbenaceae), V. inermis is a scrambling or scandent coastal shrub in the tropics and sub-tropics. From different parts of the plant, compounds such as flavonoids, diterpenes/diterpenoids, sterols, triterpenes/triterpenoids, iridoid glycosides, phenolic glycosides, phenylethanoid glycosides (PEGs), phenylpropanoid glycosides (PPGs), chalcones, and sesquiterpenes have been reported. Major pharmacological properties of V. inermis include anti-cancer, anti-inflammatory, antioxidant, hepatoprotective, analgesic, and antibacterial activities. Other properties include anti-tyrosinase, antifungal, neuroprotective, hypotensive, hypoglycemic, amyloid-β aggregation, wound healing, antipyretic, and larvicidal activities. A unique pharmacological property of V. inermis leaf extract, discovered by scientists from Taiwan, is the amelioration of motor tic disorders, a spectrum of Tourette syndrome. This property included a case report, three in vivo studies, and one patent. Areas of further research of V. inermis are suggested.
کلیدواژه ها:
نویسندگان
Eric Wie Chiang Chan
Faculty of Applied Sciences, UCSI University, ۵۶۰۰۰ Cheras, Kuala Lumpur, Malaysia
Siu Kuin Wong
School of Foundation Studies, Xiamen University Malaysia, Bandar Sunsuria, ۴۳۹۰۰ Sepang, Selangor, Malaysia
Hung Huck Chan
Secretariat of International Society for Mangrove Ecosystems (ISME), Faculty of Agriculture, University of the Ryukyus, Okinawa ۹۰۳-۰۱۲۹, Japan