Investigation of Drug Release from a Biodegradable Biphasic Polymer System

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 52

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شناسه ملی سند علمی:

JR_EJST-2-1_001

تاریخ نمایه سازی: 28 آذر 1402

چکیده مقاله:

In this study, a controlled drug delivery system was modeled to release the drug dissolved in a polymer matrix by polymer degradation. This system is in the form of a page. The drug is released into the environment by the mechanism of penetration and degradation of the polymer. What comes to mind when you first hear the name of the drug may be nothing more than pills, capsules or ampoules! While the world of medicine and the methods of its delivery to the body are not limited to these. Drugs usually enter the body in both digestive and non-digestive ways. The introduction of drugs from these methods has problems and limitations, and for this reason, researchers were looking for ways that could solve the above problems to a large extent. Following these efforts, controlled drug delivery systems were introduced, which have many benefits. The most important of these advantages include the ability to maintain the drug concentration at a relatively constant level for a certain period of time, the ability to adjust the drug release rate depending on the drug delivery site, the ability to deliver the drug to a specific organ or tissue, the ability to deliver multiple drugs with one formulation. These systems have revolutionized the treatment of many diseases and are evolving.

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نویسندگان

Maryam Milani Fard

Researcher at the Anesthesia and Pain &Molecular and cell Biology Research cente, Faculty of Medicine Department of Anatomy, Iran university of Medical Sciences, Tehran, Iran.

Amir Mohammad Milani Fard

Graduate of nursing, School of nursing and medical emergency, Alborz University of Medical ‎Sciences, Researcher of Baqiyatallah Hospital Research Center,‎ Tehran, Iran.

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  • A. Bozorgian, S. Zarinabadi, A. Samimi, Journal of Chemical Reviews, ...
  • A. Bozorgian, Journal of Engineering in Industrial Research, ۲۰۲۰, ۱, ...
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