A Facile and Efficient Synthesis of Tetrahydrobenzo[b]pyrans Using Sucrose as Green, Inexpensive, Natural and Biodegradable Catalyst

A very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under ۸۰ °C using sucrose as natural and biodegradable catalyst in water. This method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. Therefore, this methodology is entirely green and environmentally benign protocol for the preparation of tetrahydrobenzo[b]pyran derivatives.

کلیدواژه ها:

sucrose ، Malononitrile ، Multi-component reactions (MCRs) ، Tetrahydrobenzo[b]pyran