بررسی فراوانی کم خونی فقر آهن عملکردی در بیماران همودیالیزی

Aims : Anemia is one of the main problems in hemodialysis patients, which is caused by inadequate production of erythropoietin. Functional iron deficiency (FID) anemia is a kind of anemia, which lack of functional iron therein leads to resistance and inappropriate response to erythropoietin in hemodialysis patients. Since early diagnosis of this anemia before erythropoietin usage is important, this study was conducted “to determine p revalence of functional iron deficiency in hemodialysis patients”. Methods: In a cross–sectional design studied ۱۸۴ patients with chronic kidney disease referred to hemodialysis units in Baqiyatallah and Chamran hospitals in Tehran. In order to data collecting were measured serum Hb, Hct and Ferritin levels plus to completing the demographic questionnaire. The χ۲-test, T-test and ANOVA were used in this study. The data were analyzed via the SPSS۱۸ software (version). The p value of ۰.۰۵ was considered as significance level. Results: The mean of serum levels of Hb and Hct was respectively ۱۰.۹۸±۱.۷ g/dl and ۳۴.۱±۵.۲%. Anemia was observed in ۳۷%, hyperferritinemia in ۸۰.۴% and functional iron deficiency anemia in ۴۱.۱% of patients. Conclusions: Functional iron deficiency was observed in about half of hemodialysis patients and could cause resistance and inappropriate response to Erythropoetin in them. Therefore nurse awareness and his/her duly action in determining the status of iron stores prior to the administration of erythropoietin prevents from prescribing an expensive drug and imposing unnecessary costs to the patient and the health care system.