The Effect of Intrauterine Cephapirin on Treatment of Endometritis in Commercial Dairy Cattle

To evaluate the effect of intrauterine cephapirin on treatment of endometritis ۳۹ Holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. In experiment ۱, ۶ out of ۱۴ cows were ۲۵ to ۳۰ days after parturition were treated by intrauterine oxytetracycline. Another ۸ cows were treated by intrauterine cephapirin (Metri-Care). In experiment ۲, ۲۵ cows that were ۵۵-۶۰ days after parturition received three types of treatment. ۶ cows were received only PGF۲α, ۹ cows were received PGF۲α and procaine penicillin G, and ۱۰ cows were treated by intrauterine Metri-Care. Cervical mucosa was collected before and after each treatment. There was no significant difference between mean (±SD) of neutrophils before and ۱۴ days after treatment with them. Conception rates of cows received oxytetracycline and Metri-Care were ۶۶.۶۶% (۴/۶) and ۳۷.۵% (۳/۸), respectively. There was significant difference between mean of neutrophils before and ۱۴ days after treatment at all groups. Conception rate of cows received only PGF۲α was ۳۳.۳۳ % (۲/۶) and in cows received penicillin and PGF۲α was ۵۵.۵۵% (۵/۹) but in cows received Metri-Care was ۹۰.۰% (۹/۱۰). Therefore, Metri- care may be good choice for treatment of postpartum uterine infection in cow.

کلیدواژه ها:

endometritis ، cephapirin ، neutrophils ، cervical mucosa ، penicillin ، Oxytetracycline