Effect of Tissue Composition on Dose Distribution in Electron Beam Radiotherapy
محل انتشار: مجله فیزیک و مهندسی پزشکی، دوره: 5، شماره: 1
سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 39
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شناسه ملی سند علمی:
JR_JBPE-5-1_003
تاریخ نمایه سازی: 30 دی 1402
چکیده مقاله:
Objective: The aim of this study is to evaluate the effect of tissue composition on dose distribution in electron beam radiotherapy.Methods: A Siemens Primus linear accelerator and a phantom were simulated using MCNPX Monte Carlo code. In a homogeneous cylindrical phantom, six types of soft tissue and three types of tissue-equivalent materials were investigated. The tissues included muscle (skeletal), adipose tissue, blood (whole), breast tissue, soft tissue (۹-components) and soft tissue (۴-component). The tissue-equivalent materials were water, A-۱۵۰ tissue-equivalent plastic and perspex. Electron dose relative to dose in ۹-component soft tissue at various depths on the beam’s central axis was determined for ۸, ۱۲, and ۱۴ MeV electron energies.Results: The results of relative electron dose in various materials relative to dose in ۹-component soft tissue were reported for ۸, ۱۲ and ۱۴ MeV electron beams as tabulated data. While differences were observed between dose distributions in various soft tissues and tissue-equivalent materials, which vary with the composition of material, electron energy and depth in phantom, they can be ignored due to the incorporated uncertainties in Monte Carlo calculations. Conclusion: Based on the calculations performed, differences in dose distributions in various soft tissues and tissue-equivalent materials are not significant. However, due to the difference in composition of various materials, further research in this field with lower uncertainties is recommended.Â
کلیدواژه ها:
نویسندگان
M Ghorbani
Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Z S Tabatabaei
Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
A Vejdani Noghreiyan
Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
H Vosoughi
Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
C Knaup
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, USA