The Hemoglobin Levels and Transfusion Intervals of Beta-Thalassemia Patients with Positive and Negative Allo-Autoantibodies
محل انتشار: مجله علوم دارویی و شیمی، دوره: 7، شماره: 5
سال انتشار: 1403
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 28
فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JMCH-7-5_007
تاریخ نمایه سازی: 18 فروردین 1403
چکیده مقاله:
Beta-thalassemia is a common cause of anemia. Blood transfusion is the primary therapy for beta-thalassemia patients in Indonesia who are at risk of developing allo-autoantibodies. These antibodies can lead to the lysis of red blood cells, resulting in a rapid decrease in hemoglobin levels and shorter transfusion intervals. This research aims to compare hemoglobin levels and transfusion intervals in beta-thalassemia patients with positive and negative allo-autoantibodies. This research is a retrospective cohort study utilizing medical record data from beta-thalassemia patients who underwent blood transfusions at Dr. Soetomo Hospital. The patients were divided into two groups: those with positive allo-autoantibodies and those with negative allo-autoantibodies. Data on hemoglobin levels and transfusion dates were collected five times consecutively between July and December, ۲۰۲۱. The hemoglobin levels of the two groups were compared using the Mann-Whitney test, while the transfusion intervals were analysed using the T-test. Data were obtained from ۵۲ beta-thalassemia patients who received transfusions, with ۲۵ (۴۸%) testing positive for allo-autoantibodies and ۲۷ (۵۲%) testing negative. It was observed that the hemoglobin levels of the two groups were not significantly different (p = ۰.۷۶۹). Similarly, the transfusion intervals of the two groups were not significantly different (p = ۰.۸۹۹). There were no significant differences in hemoglobin levels and transfusion intervals between patients with positive and negative allo-autoantibodies.
کلیدواژه ها:
نویسندگان
Marisa Setiawan
Clinical Pathology Specialization Programme, Department of Clinical Pathology, Faculty of Medicine, Airlangga University, Dr. Soetomo Hospital, Surabaya, Indonesia
Betty Agustina Tambunan
Department of Clinical Pathology, Faculty of Medicine, Airlangga University, Dr. Soetomo Hospital, Surabaya, Indonesia
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :