The effect of exercise for patients with sarcopenia

BackgroundMany clinical practice guidelines strongly recommend exercise as an intervention for patients with sarcopenia.However, the significance of exercise on patient-important outcomes in older adults with sarcopenia isinconsistent when considering available minimal important differences. To synthesize current systematic reviewand meta-analyses evidence on the efficacy of exercise on patient-important outcomes in the treatment ofsarcopenia in older adults.ResultsThis umbrella review provided a broad overview of the existing evidence and evaluated the systematic reviews'methodological quality and evidence for all these associations. In older patients with sarcopenia, moderate- tohigh-quality evidence showed that exercise intervention probably increases walking speed and improved physicalperformance (measured by TUG test); exercise may increase the muscle strength (grip strength, keen extensionstrength); but the effect size for grip strength probably too small to achieve patients important changes. Evidencefor older people with sarcopenic obesity is limited, and we found the consistent effect of exercise interventionson grip strength and usual walking speed.ConclusionExercise has a positive and important effect on physical performance for older adults with sarcopenia, whichsupports leaving the current recommendations unchanged. New systematic reviews to summarize the effect ofexercise on the quality of life are warranted to fill the current evidence gap.

کلیدواژه ها:

exercise ، sarcopenia ، meta-analyses ، umbrella review ، randomized controlled trials