Evaluation of the Diagnostic Value of Procalcitonin in Acute Pyelonephritis Indices in Patients Referred to the Hospital
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 21
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شناسه ملی سند علمی:
JR_TBSRJ-5-4_007
تاریخ نمایه سازی: 29 فروردین 1403
چکیده مقاله:
Introduction: Uncomplicated urinary tract infection (UTI) is a widespread global ailment. The aim of this investigation was to evaluate the diagnostic efficacy of procalcitonin (PCT) in discriminating acute pyelonephritis from other lower urinary tract infections.
Material and Methods: This applied research concentrated on patients with acute pyelonephritis who were referred to Hazrat Valiasr Qaemshahr Hospital. A straightforward (random) sampling technique was implemented. Leukocyte count, ESR, serum CRP, and PCT measurements were obtained from all patients.
Results: Procalcitonin demonstrated positive results in ۹۸.۵% of pyelonephritis cases and ۵% of cystitis cases, signifying a statistically significant differentiation (P=۰.۰۰۱). The diagnostic accuracy of procalcitonin was ۹۷.۷%, while its sensitivity and specificity were ۹۸.۵% and ۹۵%, respectively. A notable correlation between serum PCT and CRP levels was observed in patients with acute pyelonephritis (P=۰.۰۳۸). The serum level of PCT in patients with acute pyelonephritis did not manifest any statistically significant variances based on age, gender, or history of urinary tract infection (P > ۰.۰۵).
Conclusion: Based on the findings of this study and comparisons with existinدg research, it can be deduced that procalcitonin functions as a dependable indicator for distinguishing acute pyelonephritis from other urinary tract infections. Consequently, its utilization for this purpose is recommended. Ultimately, conducting further studies with a larger sample size and in a multicenter manner is advised to validate the findings obtained in this study.
کلیدواژه ها:
نویسندگان
Reza Yekani
Department of Biochemistry and Biophysics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
Melody Omraninava
Assistant Professor, Hospital Administration Research Center, Sari Branch, Islamic Azad University, Sari. Iran
Farzam Nasrollahnejad
Department of Medical Sciences, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
Fatemeh Ghasemi Talouki
Department of Medical Sciences, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
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