Reproductive and Menstrual Risk Factors for Endometriosis Disease: A Case-Control Study

Objectives: The endometriosis prevalence in the general population is about 7-10%. In 30% of women, endometriosis is one of the causes for primary and secondary infertility. There are various risk factors for this disease. The present study aimed to determine reproductive and menstrual risk factors of endometriosis.Materials and Methods: In this case-control study, 185 women of reproductive age with confirmed endometriosis were compared with 370 women of reproductive age that referred to the same center for other problems in terms of reproductive and menstruation risk factors for endometriosis The two groups were matched for age. Data were collected using a researcher-made questionnaire based on previous studies. Bivariate analysis was done by the chi-square test and multivariate analysis was done by the conditional logistic regression for controlling the confounder variables.Results: Based on multivariate logistic regression, early menarche age (p=0.004), no history of pregnancy (p<0.001), no child (p=0.002), no lactation history (p<0.001), high age of first lactation (p=0.029), short duration of breastfeeding (p=0.015), no regular menstruation (p<0.001), short interval between menstrual bleeding (p=0.016), prolonged Menstruation (p<0.001), dysmenorrhea (p<0.001), dyspareunia (p<0.001), and recurrent vaginitis (p<0.001) had a significant relationship with endometriosis.Conclusions: There is a relationship between some reproductive and menstrual characteristics with endometriosis. Therefore, it seems that menstrual and reproductive characteristics can predict the occurrence of endometriosis disease.

کلیدواژه ها:

Case-control study ، Reproductive characteristics ، Menstrual characteristics ، Endometriosis