Hemolytic Events in Rh Positive Neonates Born to Rh Negative Mothers
محل انتشار: مجله علمی ناباروری ایران، دوره: 2، شماره: 1
سال انتشار: 1390
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 290
متن کامل این مقاله منتشر نشده است و فقط به صورت چکیده یا چکیده مبسوط در پایگاه موجود می باشد.
توضیح: معمولا کلیه مقالاتی که کمتر از ۵ صفحه باشند در پایگاه سیویلیکا اصل مقاله (فول تکست) محسوب نمی شوند و فقط کاربران عضو بدون کسر اعتبار می توانند فایل آنها را دریافت نمایند.
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IRJN-2-1_006
تاریخ نمایه سازی: 9 مهر 1398
چکیده مقاله:
Background One of the most important cause of severe neonatal hyperbilirubinemia is hemolysis including Rh incompatibility. The aim of this study was to assess the rate of hyperbilirubinemia due to hemolysis in Rh positive neonates born to Rh negative mothers.
Methods In this retrospective study from March 1998 to February 2003, 60 icteric Rh positive newborns that were born to Rh negative mothers, were studied. The data of patients were gathered from questionnaires sheets.
Results The rate of hemolysis due to Rh incompatibility was 18.3%. The mean age of mothers was 31.9 years (SD:4.6). The mean level of hemoglobin in these patients was significantly lower (P=0.009) and serum bilirubin levels higher than nonhemolytic icteric neonates (P=0.007). The mean age of onset of jaundice in hemolytic neonates was 1.55 days (SD: 618) and in nonhemolytic patients 2.08 (SD:1.03) days. Exchange blood transfusion was performed for 23 neonates (38.3%). In 61.7% of cases no history of anti-D immunoglobulin given during pregnancy or at delivery was present.
Conclusion Due to poor prenatal care consisting of inadequate provision of anti-D immunoglobulin in Rh negative mothers, sensitization to Rh antigen in our Rh negative mothers was considerably high.
کلیدواژه ها:
نویسندگان
Farhad Heydarian
Neonatal Research Center, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Mahmood Reza Mohajer Kohestani
Neonatal Research Center, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran